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3.
Rev Med Chil ; 146(2): 183-189, 2018 Feb.
Artigo em Espanhol | MEDLINE | ID: mdl-29999154

RESUMO

BACKGROUND: Exclusive involvement of the colon or rectum in Crohn's disease, called Crohn's colitis, (CC) occurs in about 25% of these patients. AIM: To analyze early surgical results and long-term outcomes of patients undergoing surgery for CC. MATERIAL AND METHODS: Review of a prospective database, identifying patients with Crohn's disease operated between 2003 and 2015 and excluding those with ileocecal disease. We analyzed demographic data, pre and postoperative pharmacological treatment, operations, morbidity and the need for a second bowel resection at follow-up. RESULTS: We reviewed data from 28 patients aged 17 to 72 years (15 men). Twenty-seven (96.4%) had previous pharmacological treatment, 11 received monoclonal antibodies. The most common indications for surgical treatment were failure of medical treatment in 15 cases, acute severe colitis in 12 and anemia/malnutrition in eight. Total colectomy was performed in 17 (61%) patients, proctocolectomy in 8 (29%) and segmental colectomies in 3 (11%). Sixteen (57%) were operated laparoscopically. Major postoperative complications were observed in 5 (18%). Four needed a reintervention. There was no operative mortality. During a 55 months median follow-up of 27 patients, seven (26%) required a second bowel resection, one of them for recurrence. Nineteen (70%) patients had an ostomy, which was permanent in 11. Fifteen patients are without medical treatment. CONCLUSIONS: Most of the reviewed patients required total colectomy for the control of the disease with a low surgical morbidity. Two-thirds required an ileostomy, which became permanent in half of them.


Assuntos
Doença de Crohn/cirurgia , Adolescente , Adulto , Idoso , Feminino , Seguimentos , Humanos , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Estudos Prospectivos , Resultado do Tratamento , Adulto Jovem
4.
Rev. méd. Chile ; 146(2): 183-189, feb. 2018. tab
Artigo em Espanhol | LILACS | ID: biblio-961376

RESUMO

Background: Exclusive involvement of the colon or rectum in Crohn's disease, called Crohn's colitis, (CC) occurs in about 25% of these patients. Aim: To analyze early surgical results and long-term outcomes of patients undergoing surgery for CC. Material and Methods: Review of a prospective database, identifying patients with Crohn's disease operated between 2003 and 2015 and excluding those with ileocecal disease. We analyzed demographic data, pre and postoperative pharmacological treatment, operations, morbidity and the need for a second bowel resection at follow-up. Results: We reviewed data from 28 patients aged 17 to 72 years (15 men). Twenty-seven (96.4%) had previous pharmacological treatment, 11 received monoclonal antibodies. The most common indications for surgical treatment were failure of medical treatment in 15 cases, acute severe colitis in 12 and anemia/malnutrition in eight. Total colectomy was performed in 17 (61%) patients, proctocolectomy in 8 (29%) and segmental colectomies in 3 (11%). Sixteen (57%) were operated laparoscopically. Major postoperative complications were observed in 5 (18%). Four needed a reintervention. There was no operative mortality. During a 55 months median follow-up of 27 patients, seven (26%) required a second bowel resection, one of them for recurrence. Nineteen (70%) patients had an ostomy, which was permanent in 11. Fifteen patients are without medical treatment. Conclusions: Most of the reviewed patients required total colectomy for the control of the disease with a low surgical morbidity. Two-thirds required an ileostomy, which became permanent in half of them.


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Doença de Crohn/cirurgia , Complicações Pós-Operatórias , Estudos Prospectivos , Seguimentos , Resultado do Tratamento , Tempo de Internação
5.
Gastroenterol. latinoam ; 29(4): 193-199, 2018. ilus, tab
Artigo em Espanhol | LILACS | ID: biblio-1117388

RESUMO

Chylous ascites is a peritoneal collection with milky appearance, rich in triglycerides produced by the presence of thoracic or intestinal lymph in the abdominal cavity. The increasing number of surgical interventions has meant an increase of this disease in the last time. We present the case of a 39-yearsold woman with a history of a retroperitoneal cystic lesion in the abdominal ultrasound, which was a finding, and was followed up for 5 years. In the last control abdominal ultrasound showed an accelerated growth, the study was complemented with a Magnetic Resonance Imaging of the abdomen showed a retroperitoneal cystic lesion, 7 cm larger diameter in contact with aorta, left ureter and lower pole of the left kidney, suspecting malignancy, reason why its surgical resection was decided. It evolved after the surgical intervention with progressive increase of the abdominal perimeter, diffuse pain and early satiety, performing abdominal ultrasound showing a liver of normal structure with moderate ascites. The diagnostic paracentesis gave out 1,000 mL of milky-white liquid with triglycerides of 1,287 mg/dL. The diagnosis of chylous ascites was proposed, secondary to thoracic duct injury and it was managed with a diet with low intake of saturated, polyunsaturated and monounsaturated fats, with medium chain triglycerides with favorable results. The pathophysiology, etiology, nutritional and non-nutritional management of chylous ascites are discussed.


La ascitis quilosa es una colección peritoneal con apariencia lechosa, rica en triglicéridos producido por la presencia de linfa torácica o intestinal en la cavidad abdominal. El creciente número de intervenciones quirúrgicas ha significado un aumento de esta patología en el último tiempo. Se presenta el caso de una mujer de 39 años, con historia de una lesión retroperitoneal quística en la ecotomografía abdominal, que fue un hallazgo, realizándose seguimiento por 5 años. En la última ecotomografía de control presentó crecimiento acelerado por lo que se complementa estudio con una Resonancia Nuclear Magnética de abdomen que muestro lesión quística retroperitoneal de 7 cm de diámetro mayor en contacto con aorta, uréter izquierdo y polo inferior del riñón izquierdo, sospechándose malignidad, por lo que se decide su resección. Evolucionó posterior a la intervención quirúrgica con aumento progresivo del perímetro abdominal, dolor difuso y saciedad precoz, realizándose ecotomografía abdominal que muestra un hígado de estructura normal con ascitis moderada. La paracentesis diagnóstica dio salida a 1.000 mL de líquido blanquecino de aspecto lechoso con triglicéridos de 1.287 mg/dL. Se planteó el diagnóstico de ascitis quilosa, secundario a lesión del conducto torácico y se manejó con dieta con bajo aporte en grasas saturadas, poliinsaturadas y monoinsaturadas, con aporte de triglicéridos de cadena media con resultados favorables. Se discuten la fisiopatología, etiología, manejo nutricional y no nutricional de la ascitis quilosa.


Assuntos
Humanos , Feminino , Adulto , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/etiologia , Ascite Quilosa/diagnóstico , Ascite Quilosa/etiologia , Complicações Pós-Operatórias/terapia , Ducto Torácico/lesões , Ascite Quilosa/terapia , Diagnóstico Diferencial
6.
Gastroenterol. latinoam ; 28(2): 63-69, 2017. ilus, tab, graf
Artigo em Espanhol | LILACS | ID: biblio-1118079

RESUMO

BACKGROUND: The use of endoscopic ultrasound with fine needle aspiration (EUS-FNA) has improved the characterization and staging of pancreatic solid masses. The primary strategy for improving the ability to diagnose malignant masses is the use of rapid on site evaluation (ROSE) by a cytopathologist. OBJECTIVE: To evaluate the diagnostic yield of EUS-FNA after the implementation of ROSE in an academic center. MATERIAL AND METHODS: Prospective enrollment and follow-up of EUS-FNA with ROSE during 2015 and 2016, was compared to EUS-FNA without ROSE in previous years (2011-2014) in Hospital Clínico UCChristus. Clinical and endosonographic features, cytopathological and histological diagnosis and number of passes per procedure were evaluated. All EUS-FNA included cytology and cellular block for definitive diagnosis. RESULTS: 59 pancreatic solid masses were included in the analysis. 44 EUS-FNA were performed with ROSE, compared with 15 EUS-FNA without ROSE. The mean age of patients included was 62.8 years, 54.2% male gender, and most masses studied were in the head of pancreas (77.6%). In EUS 86.5% were hypoechoic and 56.9% had poor defined margins. No differences in baseline characteristics were observed between groups. EUS-FNA led to diagnosis in 86.2% of the overall sample. The diagnostic rate was superior in the group of EUS-FNA with ROSE, compared to EUS-FNA without ROSE (97.7% vs 50%, p < 0.0001). The mean number of passes was inferior in EUS-FNA ROSE (+) (2.71 vs 5.78, p < 0.0001). No differences in rate of complications were observed between groups. CONCLUSION: The use of ROSE associated to EUS-FNA improves the diagnostic yield in the evaluation of pancreatic solid masses. Our findings are consistent with those described in the literature, recommending the use of ROSE in EUS-FNA in centers where the diagnostic yield is less than 90% without the use of ROSE


INTRODUCCIÓN: La adquisición de tejido mediante el uso de endosonografía, con punción con aguja fina, (EUS-FNA) ha mejorado el diagnóstico de lesiones pancreáticas sólidas. La principal medida para aumentar el rendimiento diagnóstico de la EUS-FNA es la evaluación por citopatólogo próximo al lugar de punción (in situ) (técnica conocida en inglés como ROSE "rapid on-site evaluation"). OBJETIVO: Evaluar el rendimiento diagnóstico de EUS-FNA en lesiones pancreáticas sólidas posterior a la implementación de ROSE en un centro universitario. MATERIAL Y MÉTODOS: Registro prospectivo de EUS-FNA realizadas con ROSE durante el período 2015-2016, comparado con EUS-FNA con evaluación histopatológica diferida realizada entre los años 2011-2014, en Hospital Clínico UC-Christus. Se evaluaron características clínicas, endosonográficas, diagnóstico histopatológico y número de pases por procedimiento. Todas las EUS-FNA incluyeron citología y block celular para diagnóstico definitivo. RESULTADOS: Se incluyeron en el análisis 59 lesiones pancreáticas sólidas evaluadas con EUS-FNA. Seguimiento prospectivo de 44 EUS-FNA con ROSE, que fueron comparadas con 15 EUS-FNA sin evaluación in situ (retrospectivo). La muestra total incluyó individuos con un promedio de 62,8 años de edad, 54,2% hombres, donde 77,6% de las lesiones se ubicaba en la cabeza pancreática. Endosonográficamente 86,5% de las lesiones eran hipoecoicas y 56,9% tenían márgenes poco definidos. La EUS-FNA fue diagnóstica en 86,2% del total de la muestra. Las EUS-FNA realizadas con ROSE presentaron un mayor rendimiento diagnóstico respecto a las efectuadas sin evaluación in situ (97,7% vs 50%, p < 0,0001). El número de pases por procedimiento fue menor (2,7% vs 5,8%, p < 0,0001) en el grupo con ROSE. No hubo diferencias en complicaciones en ambos grupos. CONCLUSIÓN: La evaluación por citopatólogo in situ de la muestra obtenida por EUS-FNA mejora el rendimiento diagnóstico de las lesiones pancreáticas sólidas. Nuestros hallazgos apoyan el uso de ROSE asociado a EUS-FNA, siendo concordantes con las recomendaciones actuales de utilizar evaluación histopatológica in situ en EUS-FNA, especialmente en centros donde el rendimiento diagnóstico sin uso de ROSE es menor a 90%.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Pancreatopatias/patologia , Pancreatopatias/diagnóstico por imagem , Aspiração por Agulha Fina Guiada por Ultrassom Endoscópico/métodos , Neoplasias Pancreáticas/patologia , Neoplasias Pancreáticas/diagnóstico por imagem , Estudos Prospectivos , Seguimentos , Biópsia por Agulha Fina , Avaliação Rápida da Integridade Ambiental
8.
Gastroenterol. latinoam ; 27(4): 207-214, 2016. ilus, tab
Artigo em Espanhol | LILACS | ID: biblio-907638

RESUMO

Introduction: Gastric cancer (GC) is the leading cause of cancer mortality in Chile. The development ofgastric adenocarcinoma its preceded by a histopathologic cascade composed of gastric atrophy, intestinal metaplasia and gastric dysplasia. Sydney protocol has been proposed as the standard method for diagnosingthese conditions. The aim of this research study was to establish whether Sydney protocol increase thedetection of premalignant gastric lesions, as gastric atrophy and intestinal metaplasia, compared to non protocolizedendoscopies/biopsies. Methods: Upper gastroduodenal endoscopies (GDE) from Hospital Clí-nico Universidad Católica de Chile between April-May 2015 and April-May 2016 was analyzed. Patientswith histological study with 18 years-old or older were included. Patients with history of GC or malignantlesions at GDE where excluded. Detection of gastric atrophy, intestinal metaplasia and suggestive findingsof autoimmune gastritis where compared between Sydney protocol and non-protocolized endoscopies/biopsies...


Introducción: El cáncer gástrico (CG) es la principal causa de muertes por cáncer en Chile. El desarrollo del adenocarcinoma gástrico es precedido por una cascada histopatológica (gastritis; atrofia gástrica/AG; metaplasia intestinal/MI). Se ha propuesto la biopsia del cuerpo, ángulo y antro a través del protocolo de Sydney para la búsqueda de estas condiciones. Objetivo: Determinar la diferencia en la detección delesiones premalignas gástricas a través del protocolo de Sydney comparado con el estudio endoscópico habitual. Métodos: Se analizaron las endoscopias digestivas altas (EDA) realizadas en el Centro de Endoscopia Digestiva del Hospital Clínico de la Universidad Católica en los períodos entre abril y mayo del 2015 y 2016. Se incluyeron las EDA de pacientes mayores de 18 años con estudio histológico. Fueron excluidos los pacientes con antecedente personal de CG o lesiones de aspecto maligno macroscópicas. Se comparó la detección de AG, MI y gastritis autoinmune (GA) en el estudio histológico entre los pacientes con protocolo Sydney y el estudio endoscópico no protocolizado...


Assuntos
Masculino , Feminino , Humanos , Adulto , Adulto Jovem , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Biópsia/métodos , Lesões Pré-Cancerosas/patologia , Neoplasias Gástricas/patologia , Atrofia/patologia , Chile , Protocolos Clínicos , Endoscopia do Sistema Digestório , Infecções por Helicobacter/patologia , Metaplasia/patologia , Estudos Retrospectivos
10.
Rev. chil. cir ; 65(3): 228-235, jun. 2013. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-684032

RESUMO

Background: pancreatic neuroendocrine tumors (PNET) account for 1-2percent of pancreatic neoplasms. Its incidence has increased in recent years probably due to improved imaging studies. Aim: to analyze the clinical characteristics, surgical outcomes and overall survival of patients with PNET who underwent resective surgery. Methods: case series study. Data was collected from the central database and clinical records from patients with biopsy-proven PNET's who underwent surgical resection from june 2005 to june 2012. Results: twenty patients were included (10.6 percent of all pancreatic resections), 12 female, with a median age of 44 [20-77] years. Abdominal pain was the most common symptom. Two patients had a type 1 multiple endocrine neoplasia (MEN-1) syndrome. Pre-operative work up included CT, MR and/or PET/CT. Five patients had functional tumors. Five Whipple procedures, 14 distal pancreatectomies and 1 enucleation were performed. Among the postoperative complications, there were 5 type B and 1 type C pancreatic fistulas. There was no mortality. At 31 [5-90] month median follow-up, overall survival was 100%. Conclusion: PNETs represent an increasing reason for pancreatic resection in our center. Surgical resection of the tumor with negative microscopic margins is the treatment of choice.


Introducción: los tumores neuroendocrinos del páncreas (TNEP) representan el 1-2 por ciento de las neoplasias pancreáticas. Su incidencia ha aumentado en los últimos años debido probablemente a la mayor capacidad diagnóstica de los estudios por imágenes. Objetivos: analizar las características clínicas, resultados quirúrgicos y sobrevida alejada de los pacientes con TNEP operados en nuestro centro. Material y Métodos: estudio descriptivo de una serie de casos. Análisis de base de datos y registros clínicos de los pacientes con diagnóstico histológico de TNEP sometidos a cirugía resectiva en nuestro centro entre junio de 2005 y junio de 2012. Resultados: serie compuesta por 20 pacientes (10,6 por ciento de las resecciones pancreáticas), 12 de sexo femenino, con una mediana de edad de 44 (20-77) años. El dolor abdominal fue el síntoma de presentación más frecuente. Dos pacientes eran portadores del síndrome de neoplasia endocrina múltiple tipo 1 (NEM-1). La evaluación diagnóstica se realizó con CT, RM y/o PET/CT. Los tumores fueron funcionantes en 5 enfermos. Se realizaron 5 pancreatoduodenectomías (PD), 14 pancreatectomías corporocaudales (PC) y 1 enucleación. Entre las complicaciones postoperatorias, hubo 5 fístulas pancreáticas tipo B y una tipo C. No hubo mortalidad. En el seguimiento (mediana de 31 [5-90] meses), ningún paciente falleció por progresión de la enfermedad. Conclusión: los TNEP representan una patología en aumento en nuestro centro. La cirugía resectiva con márgenes microscópicos negativos es la alternativa terapéutica de elección.


Assuntos
Humanos , Masculino , Adulto , Feminino , Pessoa de Meia-Idade , Neoplasias Pancreáticas/cirurgia , Neoplasias Pancreáticas/mortalidade , Tumores Neuroendócrinos/cirurgia , Tumores Neuroendócrinos/mortalidade , Estudos de Coortes , Seguimentos , Imageamento por Ressonância Magnética , Neoplasias Pancreáticas/diagnóstico , Tomografia por Emissão de Pósitrons , Complicações Pós-Operatórias , Compostos Radiofarmacêuticos , Análise de Sobrevida , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Tumores Neuroendócrinos/diagnóstico
11.
Gastroenterol. latinoam ; 21(1): 23-26, ene.-mar. 2010. ilus
Artigo em Espanhol | LILACS | ID: lil-570402

RESUMO

Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare pathology with no more than 30 reported cases worldwide. The diagnosis requires a combination of clinical elements, imagenological and histological, and to rule out other pathologies. This is the case of a 36 year-old patient presenting anemia, abdominal pain and diarrhea related to immune manifestations with a CMUSE diagnosis. Double balloon enteroscopy was a critical tool for the diagnosis. The patient showed a good response to steroidal treatment with symptomatic remission.


La enteritis estenosante y ulcerativa multifocal idiopática (CMUSE) es una entidad poco frecuente con no más de 30 casos reportados a nivel mundial. El diagnóstico requiere una combinación de elementos clínicos, imagenológicos e histológicos, y descartar otras patologías. Presentamos el caso de una paciente de 36 años que se presenta con anemia, dolor abdominal y diarrea asociado a manifestaciones inmunológicas con diagnóstico de CMUSE. La enteroscopia Doble Balón fue una herramienta fundamental para el diagnóstico. Evolucionó con buena respuesta a tratamiento esteroidal con remisión sintomática mantenida.


Assuntos
Humanos , Feminino , Adulto , Endoscopia Gastrointestinal/métodos , Enterite/diagnóstico , Obstrução Intestinal/diagnóstico , Úlcera/diagnóstico , Diagnóstico Diferencial , Enterite/tratamento farmacológico , Intestino Delgado , Metotrexato/uso terapêutico , Obstrução Intestinal/tratamento farmacológico , Vasculite , Úlcera/tratamento farmacológico
12.
Rev. méd. Chile ; 137(11): 1469-1473, nov. 2009. ilus
Artigo em Espanhol | LILACS | ID: lil-537010

RESUMO

There is an increased incidence of celiac disease in patients with idiopathic dilated cardiomyopathy. We report a 4 7 year-old female presenting with heart failure secondary to dilated cardiomyopathy of unknown etiology. During the five months following the first hospitalization the patient had multiple hospital admissions due to decompensate heart failure. Due to a history of intermittent diarrhea and weight loss, a celiac disease was suspected. Antiendomysial antibodies were positive and there was a villous atrophy in duodenal mucosa. A gluten free diet was started with a concomitant recovery of her functional capacity. After one month of gluten free diet a new echocardiogram showed a normal left ventricle and systolic function.


Assuntos
Feminino , Humanos , Cardiomiopatia Dilatada/etiologia , Doença Celíaca/complicações , Doença Celíaca/patologia
13.
Rev. chil. cir ; 61(5): 458-462, oct. 2009. ilus
Artigo em Espanhol | LILACS | ID: lil-582105

RESUMO

Ameloblastoma is a benign rare tumor, originated in the odontogenic epithelium, is locally invasive and with high tendency to local recurrence, a variety less common is the malignant or metastasizing ameloblastoma, where more frequent sites of deployment are the lung and cervical lymph nodes, being much less frequent sites the liver and skull among others. The surgical treatment is mainly the aggressive surgery of the primary tumor and metastases. We present a case of a patient with malignant mandibular ameloblastoma with metastases in liver and lung, which was subjected to a subtotal mandibulectomy, local radiotherapy and lung and liver metastasectomy in a second time, with late recurrence of the lesion.


El ameloblastoma es un tumor poco frecuente, benigno, originado en el epitelio odontogénico, es localmente invasivo y con alta tendencia a la recurrencia local, una variedad mucho menos frecuente es el ameloblastoma maligno o que causa metástasis, donde los sitios más frecuentes de implantación son el pulmón y los linfonodos cervicales, siendo sitios mucho menos frecuentes hígado y cráneo, entre otros. El tratamiento es principalmente quirúrgico con cirugía agresiva del tumor primario y posteriormente de las metástasis. Se presenta el caso de un paciente portador de ameloblastoma mandibular maligno, con metástasis hepáticas y pulmonares, que fue sometido a una mandibulectomía subtotal y radioterapia local. Posteriormente, resección de metástasis pulmonares y hepáticas en un segundo tiempo, con recidiva de las lesiones.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Ameloblastoma/cirurgia , Ameloblastoma/patologia , Neoplasias Hepáticas/secundário , Neoplasias Mandibulares/cirurgia , Neoplasias Mandibulares/patologia , Neoplasias Pulmonares/secundário , Hepatectomia , Neoplasias Hepáticas/cirurgia , Neoplasias Pulmonares/cirurgia , Pneumonectomia
14.
Rev. chil. cir ; 61(3): 279-284, jun. 2009. ilus
Artigo em Espanhol | LILACS | ID: lil-547833

RESUMO

Dubin-Johnson syndrome (SDJ) is a rare benign autosomal recessive congenital disease that causes jaundice. We report a 71 years old male with a Dubin Jonson syndrome diagnosed at the age of 40. On a ultrasound examination and magnetic resonance imaging, a liver tumor was found, that was excised. The pathology report showed a cholangiocarcinoma. During the postoperative period, the patient had a hyperbilirubinemia that subsided slowly. There are reports of hyperbilirubinemia of difficult management after hepatectomy in patients with Dubin-Johnson syndrome.


El síndrome de Dubin-Johnson (SDJ) es una patología benigna, familiar, con carácter autosómico recesivo y de aparición poco frecuente. Consiste en un defecto en la excreción hepática de la bilirrubina conjugada que permite su entrada al canalículo biliar, manifestando un cuadro clínico de ictericia silente. La asociación de esta enfermedad con colangiocarcinoma intrahepático es excepcional, siendo difícil la sospecha precoz de este diagnóstico y también el manejo de la ictericia postoperatoria. El objetivo de este trabajo es describir un caso clínico con estas características y revisión de la literatura existente. Se presenta a un paciente de sexo masculino de 71 años de edad, con antecedente de síndrome de Dubin-Johnson diagnosticado a los 40 años. Asintomático, en exámenes de rutina se encuentra un tumor hepático en la ecotomografía abdominal, que luego se corrobora en la TAC y RNM, mide aproximadamente 10 cm de diámetro, de ubicación central y derecho. Resto de estudio no muestra diseminación. Se realiza laparoscopia diagnóstica y ecografía intraoperatoria confirmando lo visto por imágenes, y se decide convertir a laparotomía para efectuar hepatectomía derecha extendida. Biopsia rápida y diferida informan colangiocarcinoma. Evoluciona favorablemente en el postoperatorio, con hiperbilirrubinemia sostenida de lenta resolución. La asociación de hepatectomía con síndrome de Dubin-Johnson es de muy baja frecuencia, existiendo poca literatura al respecto. Se ha descrito que la hiperbilirrubinemia en el postoperatorio es de difícil manejo, sin embargo, en este caso el paciente evolucionó favorablemente sin necesidad de alguna terapia específica.


Assuntos
Humanos , Masculino , Idoso , Colangiocarcinoma/cirurgia , Colangiocarcinoma/complicações , Icterícia Idiopática Crônica/complicações , Neoplasias Hepáticas/cirurgia , Neoplasias Hepáticas/complicações , Evolução Clínica , Hepatectomia , Período Pós-Operatório
15.
Rev Med Chil ; 137(11): 1469-73, 2009 Nov.
Artigo em Espanhol | MEDLINE | ID: mdl-20098806

RESUMO

There is an increased incidence of celiac disease in patients with idiopathic dilated cardiomyopathy. We report a 4 7 year-old female presenting with heart failure secondary to dilated cardiomyopathy of unknown etiology. During the five months following the first hospitalization the patient had multiple hospital admissions due to decompensate heart failure. Due to a history of intermittent diarrhea and weight loss, a celiac disease was suspected. Antiendomysial antibodies were positive and there was a villous atrophy in duodenal mucosa. A gluten free diet was started with a concomitant recovery of her functional capacity. After one month of gluten free diet a new echocardiogram showed a normal left ventricle and systolic function.


Assuntos
Cardiomiopatia Dilatada/etiologia , Doença Celíaca/complicações , Doença Celíaca/patologia , Feminino , Humanos
16.
Rev. chil. cir ; 60(4): 310-314, ago. 2008. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-510441

RESUMO

Introducción: Entre un 30-40 por ciento de los Adenomas Vellosos (AV) rectales pueden presentar cáncer, lo que clínicamente puede no ser evidente, e incluso la biopsia endoscópica puede resultar negativa. Comunicaciones recientes sugieren que la Endosonografía Rectal (ER) sería un método apropiado para detectar focos de carcinoma invasor en AV. Objetivo: Evaluar la utilidad de la ER en la detección de focos de carcinoma invasor en AV y su eventual compromiso ganglionar. Material y método: Se analizaron en forma consecutiva 1400 ER, realizadas entre Febrero del 2000 y Julio del 2006 en el Hospital U.C. Se seleccionaron aquellas ER informadas como AV rectal. El informe de ER en cuanto a la extensión del tumor en la pared y el compromiso ganglionar (uT, uN) fue comparado con el informe de anatomía patológica de la pieza quirúrgica (pT, pN). Resultados: En 28 de los 35 pacientes con ER informadas como AV rectal se pudo contar con el estudio anatomopatológico y son quienes constituyen esta serie. En 17 pacientes se encontró cáncer invasor en el estudio anatomopatológico (60,7 por ciento). La concordancia entre ER y el estudio patológico para identificar focos de cáncer en AV fue 82 por ciento. El VPP fue 100 por ciento, el VPN 69 por ciento, la sensibilidad 71 por ciento y la especificidad 100 por ciento. La concordancia para diferenciar lesiones T0-T1 de lesiones más profundas fue 75 por ciento, y para establecer invasión ganglionar fue 84 por ciento. Conclusión: La ER permite una adecuada detección de focos de cáncer en AV junto a una apropiada etapificación.


Background: Thirty to forty percent of villous adenomas can be an occult carcinoma. Even biopsy can miss the diagnosis. Rectal endosonography can be useful to detect these malignant tumors. Aim: To assess the usefulness of rectal endosonography to detect invasive carcinoma and eventual lymph node involvement in villous adenomas. Material and methods: Retrospective review of 1400 rectal endosonographies performed between years 2000 and 2006. Those cases in which a rectal villous adenoma was informed, that were subjected to surgical excision and that had a pathology report were included in the study. Results: Thirty five rectal endosonographies were informed as rectal villous adenoma and 28 had a pathology report. In 17 of the latter, an invasive carcinoma was detected on pathology. The concordance between pathology and rectal endosonography to detect the carcinoma was 82 percent. Positive and negative predictive values, sensitivity and specificity of endosonography to detect carcinoma were 100, 69, 71 and 100 percent respectively. The concordance to differentiate T0-T1 lesions from deeper lesions and to detect lymph node involvement was 75 and 84 percent respectively. Conclusions: Rectal endosonography is useful to detect carcinomas in villous adenoma and to determine the stage of such tumors.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso de 80 Anos ou mais , Adenoma Viloso/patologia , Adenoma Viloso , Endossonografia/métodos , Neoplasias Retais/patologia , Neoplasias Retais , Estadiamento de Neoplasias/métodos , Invasividade Neoplásica , Neoplasias do Colo/patologia , Neoplasias do Colo , Valor Preditivo dos Testes , Sensibilidade e Especificidade
17.
Rev. méd. Chile ; 136(1): 38-43, ene. 2008. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-483218

RESUMO

Background: Splenic abscesses are uncommon, appear in subjects with predisposing factors such as systemic infections and have high mortality rates. Aim: To report seven patients with splenic abscesses. Material and Methods: Retrospective review of medical records of patients with a splenic abscess treated between 1987 and 2005. Results: The records of four women and three males aged 20 to 74 years, were reviewed. The most common presenting symptoms were fever and abdominal pain and all had predisposing factors. Six patients had a leukocyte count of 19,500 x mm³. Mean erythrocyte sedimentation rate and C reactive protein values were 75 mm/h and 13.5 mg/dl. Diagnosis was made with ultrasound in two patients and CT scan in five. Six patients had an unique abscess and one patient had multiple lesions. A splenectomy was done in three patients as the first choice treatment and in one, due to medical treatment failure. In two patients, a CT guided percutaneous drainage was performed and one patient was subjected to medical treatment only. Abscess cultures were positive in 50 percent of patients subjected to percutaneous drainage and in 50 percent of splenectomized patients. No patient died and no complications were observed in the early or ¡ate postoperative period. Conclusion: Splenic abscesses are associated to predisposing conditions. The first choice is surgical treatment, but percutaneous drainage is also a therapeutic option.


Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Abscesso Abdominal/cirurgia , Esplenopatias/cirurgia , Abscesso Abdominal/diagnóstico , Drenagem , Estudos Retrospectivos , Esplenectomia , Esplenopatias/diagnóstico
18.
Rev. chil. cir ; 59(6): 430-435, dic. 2007. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-482848

RESUMO

Introducción: La hepatectomía extendida, definida como la resección de 5 o más segmentos hepáticos, se ha asociado a un elevado riesgo perioperatorio. El objetivo del presente estudio es comparar los resultados quirúrgicos de pacientes sometidos a resecciones hepáticas de más de 2 segmentos versus hepatectomía extendida. Material y Método: Se analizó nuestra serie prospectiva de pacientes entre agosto 2002 y junio 2005. Se excluyeron resecciones laparoscópicas, unisegmentarias y no anatómicas. Se configuraron 2 grupos: Grupo I: Hepatectomías extendidas, Grupo II: Resecciones hepáticas de 2 a 4 segmentos. Se analizaron variables demográficas, indicaciones, uso de hemoderivados, función hepática postoperatoria, morbilidad y mortalidad. Resultados: En este período se realizaron 59 hepatectomías. Veintinueve cumplieron los criterios de inclusión. Grupo I: (n=14,) Grupo II: (n=15). Todos los pacientes del primer grupo fueron resecados por lesiones malignas (9 metástasis, 5 tumores primarios). El promedio de segmentos resecados fue 5.5 para el grupo I y 2.3 para el Grupo II. Los tiempos operatorios promedio fueron 283 y 199 minutos, respectivamente (p=0.025). Se transfundieron un promedio de 2.69 y 0.85 U GR en cada grupo (p=0.009). La estadía hospitalaria promedio fue 13.6 días para el primer grupo, y 7.35 para el segundo (p=0.004). En el Grupo I, 4 de 14 pacientes presentaron complicaciones quirúrgicas y 1 de 15 en el grupo II (p=0.1). Fallece un paciente de cada grupo, debido a insuficiencia hepática postoperatoria. Conclusiones: A pesar del gran volumen de parénquima resecado, la hepatectomía extendida es una alternativa segura para el tratamiento de lesiones hepáticas malignas.


Introduction: Extended hepatectomy has been associated with a high perioperative risk. The aim of this study is to compare the surgical results in patients who underwent a hepatic resection of more than two Couinaud's segments versus an extended hepatectomy (more than four segments). Methods: Our prospective database from August 2002 to June 2005 was reviewed. Non-anatomical, unisegmental and laparoscopic resections were excluded. There were two groups. Group I: Extended hepatectomies; Group II: Hepatic resections from 2 to 4 segments. Demographic characteristics, indications for surgery, technical aspects, use of hemocomponents, post-operative liver function, morbidity and mortality were reviewed. Results: In this period, 59 hepatectomies were performed. 29 procedures achieved the inclusion criteria. Group I: (n=14), Group II: (n=15). Hepatobiliary malignancy was the surgical indication in all cases in Group I (9 liver metastases, 5 primary liver tumors). Mean number of resected segments were 5.5 for Group 1, and 2.3 for Group II. Mean operative time was 283 and 199 minutes, respectively (p=0.025). Mean red blood cell units transfused were 2.69 and 0.85 in each group (p=0.009). Mean postop hospital stay was 13.6 days por the first group and 7.3 for the second group (p=0.004). In Group I, 4 of 14 patients developed a postoperative complication and 1 of 15 in Group II (p=0.1). Postoperative liver failure was present in two patients from Group I, one of them died. In Group II, 1 patient died secondary to liver failure. Conclussions: Extended hepatectomy is a safe procedure for hepatobiliary malignancy even when a large amount of liver parenchyma is resected.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Hepatectomia/métodos , Neoplasias Hepáticas/cirurgia , Neoplasias dos Ductos Biliares/cirurgia , Chile/epidemiologia , Cuidados Pós-Operatórios/mortalidade , Hepatectomia/estatística & dados numéricos , Complicações Pós-Operatórias , Estudos Prospectivos , Fatores de Tempo
19.
Rev. chil. cir ; 59(5): 360-365, oct. 2007. tab
Artigo em Espanhol | LILACS | ID: lil-477318

RESUMO

Introducción: Se denomina pancreatectomía distal a la resección pancreática a la izquierda del eje mesentérico portal. Los objetivos del trabajo son analizar las indicaciones y los resultados quirúrgicos de esta operación en enfermos con un tumor pancreático. Material y métodos: Estudio retrospectivo de 38 pacientes operados entre 1990 y 2005. Se analizaron las características clínicas, quirúrgicas y el estudio anatomopatológico. Resultados: Se operaron 29 mujeres y 9 hombres, de 52,9 + 5 años. El motivo de consulta más frecuente fue dolor abdominal en 26 enfermos. El diagnóstico se realizó con una ecografía en 7 pacientes y en 31 con una tomografía o una resonancia de abdomen. La indicación quirúrgica fue la presencia de un tumor pancreático en los 38 enfermos, quístico en 24 y sólido en 14. A 25 pacientes se les realizó una esplenectomía. Diez enfermos presentaron complicaciones postoperatorias; las más frecuentes fueron: fístula pancreática en 5, sepsis en 3 e infección del catéter central en 3. No hubo diferencias en la frecuencia de complicaciones ni en el desarrollo de una fístula pancreática entre los enfermos con y sin esplenectomía. Un enfermo falleció por sepsis abdominal. El estudio anatomopatológico mostró 28 tumores benignos y 10 tumores malignos, siendo los más frecuentes el cistoadenoma mucinoso y el adenocarcinoma, respectivamente. Conclusiones: Las pancreatectomías distales se realizaron principalmente por un tumor quístico benigno. La complicación más frecuente fue la fístula pancreática, la que llevó a la muerte a un paciente. Los enfermos esplenectomizados no presentaron más complicaciones postoperatorias que los sin esplenectomía.


Background: Resection of the pancreatic portion located to the left of the portal mesenteric axis is called distal pancreatectomy Aim: To analyze the indications and surgical results of distal pancreatectomy in patients with pancreatic tumors. Material and methods: Retrospective review of medical records of patients subjected to a distal pancreatectomy for pancreatic tumors, between 1990 and 2005. Patient features, and early complications were evaluated. Results: In the study period, 38 patients aged 53 + 5 years (29 females), were operated. The tumor was cystic in 24 patients and solid in 14. Ten patients had postoperative complications. The most common complications were pancreatic fistula in five patients, sepsis in three and catheter infection in three. No differences in the rate of complications or development of pancreatic fistula, were observed between patients subjected or not subjected to splenectomy. One patient died due to abdominal sepsis. Pathology showed 28 benign tumors (mucinous cystadenoma the most common) and 10 malignant tumors (adenocarcinoma the most common). Conclusions: The most frequent complication of distal pancreatectomy was pancreatic fistula. One patient died as a consequence of this complication. Patients subjected to splenectomy did not have a higher rate of complications.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Neoplasias Pancreáticas/cirurgia , Pancreatectomia/efeitos adversos , Pancreatectomia/métodos , Fístula Pancreática/etiologia , Neoplasias Pancreáticas/patologia , Complicações Pós-Operatórias , Reoperação , Estudos Retrospectivos , Esplenectomia , Sepse/etiologia
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